METABOLISM OF DOXAPRAM IN PREMATURE NEWBORNS
نویسندگان
چکیده
منابع مشابه
Theophylline toxicokinetics in premature newborns.
BACKGROUND While cytochrome P4501A2 is the primary pathway for theophylline (aminophylline ethylenediamine) metabolism in adults, it is developmentally immature in the newborn. OBJECTIVE To report the developmental differences in theophylline toxicokinetics of neonates. DESIGN Case series. Three premature neonates received inadvertent intravenous overdoses of theophylline for apnea of prema...
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Introduction MRI techniques have recently demonstrated the ability to provide valuable anatomic imaging in the newborn brain, but additional metabolic markers would be important to provide improved assessments of neonatal brain injury. 3D point-resolved spectroscopic imaging (PRESS-MRSI) can provide accurate measurements of metabolite levels throughout the brain, but it is more complex than com...
متن کاملPopulation pharmacokinetics of gentamicin in premature newborns.
OBJECTIVES To determine the pharmacokinetic parameters of gentamicin in a population of 200 premature newborns and to investigate the influence of several clinical and physiopathological covariates on the pharmacokinetics of the drug. To validate the pharmacokinetic analysis performed in another population of 50 premature newborns. METHODS A total of 200 premature newborns were evaluated at t...
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Neonatal liver abscess is a very rare condition associated with high morbidity and mortality rates. There seems to be an increasing trend of this rare condition amongst the newborns admitted to neonatal intensive care units. We report a case of liver abscess in a premature newborn and briefly review the literature and discuss its management.
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Preterm newborns are highly susceptible to brain injury. White matter injury is among the dominant patterns of brain injury in preterm newborns. the purpose of this review is to discuss the pathogenesis, diagnosis, management, and prevention of white matter injury in premature newborns. the long-term outcome of white matter injury in children born prematurely is also addressed.
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1987
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198704010-00394